Saturday, 12 October 2019
Conference room Punente


9:00-9:15 Welcome & General Introduction

Invited Experts Talks (~20min + 10min Q&A)
9:15-9:45 M. MacLeod: All the (good) reasons why you should do a pRCT in sepsis
9:45–10:15 P. Kochanek: Lessons from the OBTT: Do’s and Don’t’s in planning/executing a pRCT

10:15-10:30 Coffee Break

Block 1 (120min):
10:30-11:30 Presentation of drug candidates, discussion and voting
11:30-12:30 Study design for pRCT – Part 1 (the drug, SB-1/2 & EG-1/2 & study endpoints)

12:30-13:30 Lunch (Basilico restaurant)

Block 2 (105min):
13:30-13:45 J. Lederer: Doing Dirty Pre-Clinical Research
13:45-14:15 Study design for pRCT – Part 2 (choosing strains, sex, age & humane endpoints)
14:15-14:45 Who-does-what/where: defining the models/center blocks 1 & 2 allocation
14:45-15:15 pRCT Logistics – Part 1 (central analytical hubs)

15:15-15:30 Coffee Break

Block 3 (90min):
15:30-16:00 pRCT Logistics – Part 2 (data storage & analysis)
16:00-16:30 pRCT Public Relations & dissemination
16:30-16:45 All the (other) important issues that we did not discuss so far…

16:45-17:00 Summary & Conclusions
17:00-18:00 ER time-slot for super-urgent topics (that no one really wants to stay for)

19:00 Dinner at Taverna Diktina (650m from Avra)